Tissue plasminogen activator (tPA) is a naturally occurring protein in the body that activates plasmin, the main enzyme responsible for dissolving blood clots (fibrinolysis). In medical use, tPA refers to recombinant forms of this protein (such as alteplase, tenecteplase, and reteplase) that are administered as medicines to break down dangerous blood clots in emergencies. tPA … Read more
Thrombolytic therapy refers to the use of medicines that dissolve blood clots by activating the body’s natural fibrinolytic system. These medicines are given intravenously (into a vein) or occasionally intra-arterially (directly into the blocked artery) to restore blood flow through an obstructed vessel. Thrombolytic agents include alteplase, tenecteplase, reteplase, and streptokinase. They work by activating … Read more
to treat high blood pressure and heart failure, also used to help prevent heart, kidney or blood vessel problems in people who are at risk of these